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aGLP-1 receptor agonists & anesthesia: ( practical perioperative approach you can actually use) GLP-1 receptor agonists (e.g., semaglutide, liraglutide, dulaglutide, tirzepatide) are now routine in patients presenting for procedures
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Notably, while GLP-1 can potentially affect glucagon secretion via its stimulatory effect on the β-cells in normal physiological conditions, GLP-1 also inhibits glucagon release in type 1 diabetes, thus demonstrating that GLP-1 inhibition of glucagon secretion does not fully depend on the β-cell secretome [516]
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